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Functional mimics of superoxide dismutase enzymes as therapeutics agents

Article Abstract:

Several manganese complexes can mimic the action of superoxide dismutase, which eliminates free radicals. The most effective are Mn(super III)(salen) complexes and Mn(super II)([15]aneN(sub 5)) complexes.

Author: Riley, Dennis P.
Publisher: American Chemical Society
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 1999
Prevention, Manganese, Manganese (Metal), Free radicals (Chemistry), Free radicals

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Non-platinum chemotherapeutic metallopharmaceuticals

Article Abstract:

Researchers continue to investigate chemotherapeutic drugs containing other transition metals besides platinum. These investigational drugs are based on ruthenium, rhodium, titanium, vanadium, and tin.

Author: Clarke, Michael J., Zhu, Fuchun, Frasca, Dominic R.
Publisher: American Chemical Society
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 1999
Research, Antineoplastic agents, Transition metal compounds

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Subjects list: Health aspects, Inorganic compounds
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