A multicompartmental model which simulates the Thallium-201 exercise stress test
Article Abstract:
Thallium-201 exercise stress testing is a standard method of identifying ischermia of coronary artery disease, but no model exists for simulating the test. We have developed such a model using compartmental analysis methods. Blood samples were obtained from resting dogs following IV Tl-201 administration, and fitted by a sum of four exponentials, indicative of a four compartment system. The intercompartmental rate constants were estimated from fitting blood, heart and urinary excretion data using a table top computer; a best fit was obtained by non-linear least squares regression. By partitioning the heart into normal flow and ischemic zones, the effects of varying blood flow during treadmill exercise could be simulated, by summing resting flow and increased flow whose duration was varied by a damping circuit and delay line. Progressively decreasing flow in the perturbed model reproduced the abnormal Tl-201 distribution seen clinically by scanning, and experimentally. This model appears to be a useful simulation of the Tl-201 exercise stress test. (Reprinted with permission of the publisher.)
Publication Name: SIMULATION
Subject: Engineering and manufacturing industries
ISSN: 0037-5497
Year: 1992
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A port simulation model for bulk cargo operations
Article Abstract:
A port simulation model (Monte Carlo type) is presented to simulate the future economic port capacity to meet projected cargo demand. The first part of the model determines the effects caused by the port capacity expansion. The second part evaluates the port economics due to changes in the port capacity. The simulation model was tested by applying it to the actual port expansion followed at the Port of Mobile in Alabama. (Reprinted by permission of the publisher)
Publication Name: SIMULATION
Subject: Engineering and manufacturing industries
ISSN: 0037-5497
Year: 1987
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AF AGILEly Simulates A-7D Rough Runway Operations
Article Abstract:
Researchers at Wright-Patterson Air Force Base have developed a rough runway simulator called AGILE (Aircraft Ground Induced Loads Excitation). The AGILE equipment can simulate hitting bumps one to three inches high at speeds of up to 230 mph, and can withstand loads of up to 100,000 pounds. AGILE has been used to test the A-7D and the YF-16 aircraft. A photograph of the AGILE facility is included.
Publication Name: SIMULATION
Subject: Engineering and manufacturing industries
ISSN: 0037-5497
Year: 1985
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