Anticholesterol antibodies and plaque formation

Article Abstract:

Recent experiments with rabbits show that immunization with cholesterol liposomes can generate antibodies against cholesterol, reduce blood cholesterol levels and reduce the risk of atherosclerosis. The rabbits were given liposomes made of 71% cholesterol and a lipid A adjuvant. An anticholesterol vaccine might eventually allow the immune system to control cholesterol levels.

Evaluation, Prevention, Anticholesteremic agents, Antibodies

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Lipoprotein lipase genetic variation and gender-specific ischemic cerebrovascular disease risk

Article Abstract:

Research indicates a higher genetic predisposition for cerebrovascular diseases, specifically atherosclerosis, in women who carry a mutation in the lipoprotein lipase gene. Since the magnitude of the predisposition is equal to or less than other controllable risk factors such as hypertension, diet and lifestyle modifications can attenuate the genetic risk.

United States, Statistical Data Included, Analysis, Genetic aspects, Ischemia, Cerebrovascular disease, Cerebrovascular disorders, Genetic research, Lipoprotein lipase

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Endothelial lipase: a new member of the family

Article Abstract:

Newly-discovered endothelial lipase may play a significant role in plasma high-density lipoprotein metabolism. Lipases hydrolyze triglycerides, cholesterol esters, and phospholipids.

Research, Heart, Lipase

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