ACE inhibitor bulks up muscle

Article Abstract:

Losartan, an inhibitor of angiotensin II type I receptor (AT1) and an FDA-approved drug commonly used to treat high blood pressure, is found to block TGF-[beta] signaling in skeletal muscle. Losartan treatment has provided a promising method to improve pathology in Marfan syndrome and other myopathies and new insights into the study of basic pathological mechanisms underlying various disorders of muscle.

Health aspects, United States. Food and Drug Administration, Losartan, Skeletal muscle

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Sex and the genetic diversity of HIV-1

Article Abstract:

The differences between males and females with regards to the pathogenesis of human immunodeficiency virus type 1 (HIV-1) are discussed. Topics addressed include the genetic variability of HIV-1, the efficiency of HIV transmission, and how drugs and vaccines can respond to the diversification of HIV-1.

Methods, HIV infection, HIV infections, Genetic aspects, HIV patients, Disease transmission, Viral research, Virus research, AIDS (Disease)

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Not a minute to waste

Article Abstract:

This article discusses the progress of research in understanding the signaling pathways that regulate both muscle development and decay. The author maintains that with a better understanding the ability to repair injured and diseased muscles improves.

Care and treatment, Muscle diseases, Muscular diseases

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