Cardiovascular risks of antiretroviral therapies
Article Abstract:
The use of highly active antiretroviral therapy (HAART) has led to sustained reductions in mortality from HIV infection, but it is also associated with metabolic complications that might increase patients' cardiovascular disease risk. It is revealed that considerable progress is made in the development of newer antiretroviral therapies that have a better metabolic profile relating to dyslipidemia, hyperglycemia, and lipodystrophy.
Publication Name: Annual Review of Medicine
Subject: Health
ISSN: 0066-4219
Year: 2007
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Angiogenesis in ischemic and neoplastic disorders
Article Abstract:
This article presents a critical review of clinical evaluations of novel therapeutic approaches for stimulating angiogenesis in ischemic tissue and its inhibition in cancerous tissue. Angiogenesis is triggered by the hypoxia-inducible factor 1 mediated production of vascular endothelial growth factor involved in the advent of angiogenesis.
Publication Name: Annual Review of Medicine
Subject: Health
ISSN: 0066-4219
Year: 2003
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Current concepts in thrombotic thrombocytopenic purpura
Article Abstract:
A study is conducted to review the characteristics and function of a circulating zinc metalloprotease, ADAMTS13, whose deficiency causes thrombotic thrombocytopenic purpura (TTP). Results show that the identification of ADAMTS13 raises the possibility of providing molecular therapy for the treatment of TTP.
Publication Name: Annual Review of Medicine
Subject: Health
ISSN: 0066-4219
Year: 2006
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