A prospective study of first-incidence depression: the Lundby study, 1957-72

Article Abstract:

Incidence studies of disease are not often undertaken because of the time requirement and the size of the sample required for results that can be generalized to the population. The study of depression is no exception in this regard. Most studies that have looked at the occurrence of depression have done so from a prevalence point of view. To help fill the void of incidence studies, 2,612 individuals, making up a fair representation of the larger town from which they came, were psychiatrically evaluated in 1957 and followed for the next 15 years. Each subject was interviewed at the beginning of the study and again at the end. The interview focused on mental health and additional information was obtained from relatives, hospital records, or other means. Of the subjects, 124 were diagnosed as depressed or had a history of depression at the start of the study. Two hundred five had their first incidence of depression in the study period. Standardized for age, the annual first-incidence statistics for depression were 4.3 per 1,000 person-years in men, and 7.6 per 1,000 person-years in women. These rates differ from those found in other studies. More than 25 percent of men living to 70 years old and nearly 50 percent of the women experienced at least one clinically relevant depression during their lifetime. This suggests that the average person runs a high risk of developing depression at some time or other. It is possible that prognostic information may be found upon further analysis of the data. (Consumer Summary produced by Reliance Medical Information, Inc.)

Sweden, Diagnosis, Statistics, Depression, Mental, Depression (Mood disorder), Affective disorders, Mood disorders

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Persistent leukocytosis in an elderly woman

Article Abstract:

Persistent leukocytosis in an 80-year-old white woman was apparently successfully managed, although no definite cause for her condition was discovered. The woman was admitted to a hospital for treatment of cellulitis but was found to have an elevated leukocyte count. She was treated with cefazolin, ciprofloxacin, vancomycin, cefaperazone and minocycline. A detailed medical history might have permitted more thorough understanding of this case.

Health aspects, Care and treatment, Aged, Elderly, Medical history taking, Leukocytosis

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