Abstracts » Health

Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy

Article Abstract:

The antihypertensive drug losartan can slow the progression of kidney disease in people with type 2 diabetes and high blood pressure, according to a study of 1,513 patients. This drug belongs to a new class of drugs called angiotensin II-receptor blockers.

Evaluation, Prevention, Complications, Angiotensin II receptor blockers, Losartan

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Development and progression of renal disease in Pima indians with non-insulin-dependent diabetes mellitus

Article Abstract:

The development of kidney disease in Pima indians with non-insulin-dependent diabetes mellitus (NIDDM) appears to be similar to that seen in other diabetics. Researchers measured blood flow in the kidneys and the glomerular filtration rate in 194 Pima indians. Glomerular filtration rate is a measure of kidney function. Newly diagnosed diabetics had increased blood flow to the kidneys. Over the four-year study, the glomerular filtration rate increased in newly diagnosed diabetics, but dropped in those who were excreting albumin in their urine. This is a sign that their kidneys were damaged.

Health aspects, Pimas

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Initiation and progression of diabetic nephropathy

Article Abstract:

The initiation and progression of diabetic kidney disease appears to be similar in both insulin-dependent (IDDM) and non-insulin-dependent diabetes mellitus. This was demonstrated in a study of Pima indians published in 1996. Other studies have also shown that diabetic kidney disease and other complications of diabetes can be slowed by maintaining good control of blood glucose and using drugs that lower blood pressure. Many patients also have risk factors that can be changed such as smoking, elevated cholesterol levels and high blood pressure.

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