Effect of nitric oxide synthase inhibition on the uterine vasculature of the late-pregnant ewe

Article Abstract:

Nitric oxide appears to cause blood vessels in the uterus to relax. This relaxation of blood vessels is called vasodilation and chemicals and drugs that cause it are called vasodilators. Researchers analyzed the effect of nitric oxide in the uterus by infusing a chemical that inhibits nitric oxide production into the uterine arteries of sheep. The nitric oxide inhibitor caused uterine blood flow to decrease and increased arterial blood pressure. This confirms that nitric oxide acts as a vasodilator during pregnancy.

Nitric oxide, Uterus

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Cardiovascular and endocrine responses to cutaneous electrical stimulation after fentanyl in the ovine fetus

Article Abstract:

The effect of fentanyl analgesia on the cardiovascular and endocrine response to cutaneous electrical stimulation in the late gestation ovine fetus is investigated. The cutaneous electrical stimulation in the fetal sheep causes an increase in heart rate and fentanyl has significant effects, which might adversely affect the fetus, on the cardiovascular and endocrine system.

Science & research, Pharmaceutical Preparation Manufacturing, Narcotic Analgesic Preparations, Complications and side effects, Opioids, Electric stimulation, Analgesia

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Acute cerebral redistribution in response to invasive procedures in the human fetus

Article Abstract:

The human fetus is capable of redirecting blood flow to vital organs when it is under stress. The brain and heart in particular are protected, and this was confirmed in a study of 136 invasive fetal procedures such as blood sampling, transfusion, shunt insertion, and tissue biopsy.

Fetus, Stress (Physiology), Blood circulation

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