Effect of sulfadoxine-pyrimethamine resistance on the efficacy of intermittent preventive therapy for malaria control during pregnancy: A systematic review
Article Abstract:
The effect of increasing resistance to sulfadoxine-pyrimethamine on the efficacy of intermittent preventive therapy (IPT) during pregnancy in Africa is examined. The results have shown that in areas where1 to 4 treatments with sulfadoxine-pyrimethanime fail in children by day 14, the 2-dose IPT with sulfadoxine-pyrimethamine regimen has provided substantial benefit to HIV-negative semi-immune pregnant women.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2007
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New drug formulations offer hope for easing global burden of malaria
Article Abstract:
A new formulation of antimalarial drug that combines artesunate and amodiaquine reduces the daily number of pills taken from 8 pills to only 2 pills. Combination regimens with fewer pills can decrease the cost of treatment, improve adherence and help in preventing the development of drug resistance.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2006
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Combination therapy for uncomplicated Falciparum malaria in Ugandan children
Article Abstract:
Trials were conducted to compare the efficacy and safety of 3 leading combination therapies for the treatment of uncomplicated malaria. Artemether-lumefantrine was observed to be the most efficacious treatment for uncomplicated malaria.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2007
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