Effects of continuing or stopping alendronate after 5 years of treatment: The Fracture Intervention Trial Long-term Extension (FLEX): A randomized trial
Article Abstract:
Data from a randomized trial, the Fracture Intervention Trial Long-term Extension (FLEX), are used to evaluate the effects of continuing or stopping treatment with alendronate after 5 years on bone mineral density (BMD) and fracture risk in postmenopausal women with low BMD. Results suggest that discontinuation of alendronate for up to 5 years does not significantly increase fracture risk for many women, but women with vertebral fracture or very low BMD may benefit by continuing alendronate treatment beyond 5 years.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
A 55-year-old woman with osteopenia
Article Abstract:
Most postmenopausal women have a bone density T score at the femoral neck between -1.0 and -2.5, which is termed 'osteopenia', and this encompasses a wide range of fracture risks. A case study of a 55-year-old woman with osteopenia is presented along with the some recommendations on preventive measures and treatments.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
Effects of different doses of physical activity on cardiorespiratory fitness among sedentary, overweight or obese postmenopausal women with elevated blood pressure
Article Abstract:
The Dose-Response to Exercise in postmenopausal Women (DREW) trial is studied. The observation showed that previously sedentary, overweight or obese postmenopausal women experienced a graded dose-response change in fitness across levels of exercise training.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2007
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Effects of acadesine on myocardial infarction, stroke, and death following surgery: a meta-analysis of the 5 international randomized trials
- Abstracts: Clinical outcomes after hepatitis C infection from contaminated anti-D immune globulin. Rabbit antithymocyte globulin versus basiliximab in renal transplantation
- Abstracts: Experts Describe Optimal Symptom Management for Hospice Patients. Palliative care for frail older adults
- Abstracts: Patient-to-patient transmission of hepatitis C virus during colonoscopy. Use of the Web for Medical Information by a Gastroenterology Clinic Population
- Abstracts: Dietary protein and blood pressure. Effect of reduced dietary sodium on blood pressure: a meta-analysis of randomized controlled trials