Effects of continuing or stopping alendronate after 5 years of treatment: The Fracture Intervention Trial Long-term Extension (FLEX): A randomized trial

Article Abstract:

Data from a randomized trial, the Fracture Intervention Trial Long-term Extension (FLEX), are used to evaluate the effects of continuing or stopping treatment with alendronate after 5 years on bone mineral density (BMD) and fracture risk in postmenopausal women with low BMD. Results suggest that discontinuation of alendronate for up to 5 years does not significantly increase fracture risk for many women, but women with vertebral fracture or very low BMD may benefit by continuing alendronate treatment beyond 5 years.

Care and treatment, Usage, Risk factors, Alendronate, Fractures (Injuries), Fractures

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A 55-year-old woman with osteopenia

Article Abstract:

Most postmenopausal women have a bone density T score at the femoral neck between -1.0 and -2.5, which is termed 'osteopenia', and this encompasses a wide range of fracture risks. A case study of a 55-year-old woman with osteopenia is presented along with the some recommendations on preventive measures and treatments.

Case studies, Osteoporosis, Case study

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Effects of different doses of physical activity on cardiorespiratory fitness among sedentary, overweight or obese postmenopausal women with elevated blood pressure

Article Abstract:

The Dose-Response to Exercise in postmenopausal Women (DREW) trial is studied. The observation showed that previously sedentary, overweight or obese postmenopausal women experienced a graded dose-response change in fitness across levels of exercise training.

Science & research, Research, Overweight persons, Exercise therapy

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