Ceftriaxone-resistant Salmonella infection acquired by a child from cattle
Article Abstract:
Researchers provide evidence that the use of antibiotics in cattle feed may be responsible for drug resistance in many bacteria. When a 12-year-old boy on a Nebraska farm developed ceftriaxone-resistant Salmonella infection, the Nebraska health department began an investigation. They did this because ceftriaxone is used to treat Salmonella infection in children so resistance to the drug would be a serious public health problem. Detailed molecular analysis revealed that the boy was infected with a strain of the bacterium identical to one found in fecal material from some of the cattle on his farm.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2000
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Emergence of Domestically Acquired Ceftriaxone-Resistant Salmonella Infections Associated With AmpC [beta]-Lactamase
Article Abstract:
Salmonella is becoming resistant to the antibiotic ceftriaxone. The percentage of Salmonella isolates known to be resistant to the drug increased from 0.1% in 1996 to 0.5% in 1998. The resistance is commonly caused by a gene for drug resistance called the ampC gene.
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2000
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Multidrug resistance - a sign of the times
Article Abstract:
It is time to take a serious look at the level of antibiotic use in the US. A 1998 study reported the emergence of a strain of Salmonella that is resistant to five to seven different drugs. Salmonella normally resides in animals and the widespread use of antibiotics on farm animals may be a direct cause of multi-drug resistance in this bacterium. Inappropriate prescribing of antibiotics for viral infections has also contributed. Bacteria can also transfer genes for drug-resistance to other bacteria. The World Health Organization has called for a ban on antibiotic use in animals simply to promote growth.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1998
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