Guggulipid for the treatment of hypercholesterolemia: a randomized controlled trial

Article Abstract:

A substance called guggulipid that is derived from the resin of the mukul myrrh tree does not appear to lower cholesterol levels, according to a study of 103 people with high cholesterol levels. In fact, guggulipid actually increased blood levels of LDL cholesterol, which may be harmful. Extracts of this resin have been used medicinally since 600 BC.

Author: Rader, Daniel J., Cucchiara, Andrew J., Szapary, Philippe O., Wolfe, Megan L., Bloedon, LeAnne T., DerMarderosian, Ara H., Cirigliano, Michael D.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2003
Other Crop Farming, AGRICULTURAL PRODUCTION--CROPS, Medicinal Plants, Care and treatment, Evaluation, Hypercholesterolemia, Medicine, Herbal, Herbal medicine, Medicine, Botanic

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HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events

Article Abstract:

The relationship between the frequency of major cardiovascular events and HDL cholesterol levels in coronary heart disease patients treated with statins analyzed from the TNT trial examination is described. HDL cholesterol levels were observed to be predictive even among patients with LDL cholesterol levels below 70 mg per deciliter.

Author: Grundy, Scott M., Fruchart, Jean-Charles, LaRosa, John C., Gotto, Antonio M., Phil, D., Barter, Philip, Szarek, Michael, Maroni, Jaman, Kastelein, John P., Bittner, Vera
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
Science & research, Health aspects, Research, Complications and side effects, Cholesterol, HDL, HDL cholesterol lipoproteins, Clinical report

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Effects of an inhibitor of cholesteryl ester transfer protein on HDL cholesterol

Article Abstract:

A single-blind, placebo controlled study to examine the effects of torcetrapid, on plasma lipoprotein levels in subjects with low levels of high-density lipoprotein (HDL) cholesterol was conducted. The distribution among HDL and low-density lipoprotein (LDL) was found to be altered by torcetrapid.

Author: Rader, Daniel J., Schaefer, Ernst J., Wolfe, Megan L., Bloedon, LeAnne T., Brousseau, Margaret E., Digenio, Andres G., Clark, Ronald W., Mancuso, James P.
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2004
Analysis, Lipoproteins, Blood lipoproteins

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Subjects list: United States, Risk factors, Coronary heart disease, Dosage and administration, Statins
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