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Primary immunodeficiency diseases

Article Abstract:

Primary immunodeficiency diseases result from genetic defects, rather than from infection, malnutrition or other acquired sources. These often manifest as severe and recurrent infections that do not respond to conventional treatment. Specific immune disorders are sometimes associated with infection by particular organisms. Genetic defects can produce white cell defects, antibody deficiencies, and other immune problems. A family history of unusual illness sometimes suggests inherited immunodeficiencies. Testing can identify people at risk for passing genetic illnesses to their children.

Author: Puck, Jennifer M.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1997
Immunological deficiency syndromes, Immunologic deficiency syndromes

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Immunopathogenesis of gastrointestinal and hepatobiliary diseases

Article Abstract:

Immunologic processes play a role within the mucous membranes in several gastrointestinal and liver diseases. The immune system helps to maintain the health of the intestinal tract, but uncontrolled inflammation and immune response can contribute to inflammatory bowel diseases. Immune dysfunction may explain the ulcers that can develop in some people with Helicobacter pylori infection of the stomach. The damage of viral hepatitis may in part result from the protective immune destruction of infected liver cells. Autoimmune diseases can also damage the liver.

Author: Gershwin, M. Eric, Galperin, Claudio
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 1997
Physiological aspects, Celiac disease, Gastrointestinal diseases, Inflammatory bowel diseases, Chronic active hepatitis, Biliary cirrhosis

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