Levels of vaginal secretory leukocyte protease inhibitor are decreased in women with lower reproductive tract infections

Article Abstract:

Sexually transmitted diseases (STD) may increase the risk of HIV infection by reducing the amount of secretory leukocyte protease inhibitor in vaginal fluids. This was found in a study of 438 women, about half of whom had an STD. Secretory leukocyte protease inhibitor protects against HIV infection.

Author: Hillier, Sharon L., Heine, R. Phillip, Landers, Daniel V., Draper, Deborah L., Krohn, Marijane A., Wiesenfeld, Harold C.
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2000
Sexually transmitted diseases, Risk factors, HIV infection, HIV infections, Protease inhibitors

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Decreased cervical proinflammatory cytokines permit subsequent upper genital tract infection during pregnancy

Article Abstract:

The authors have tested the hypothesis that suppression immune function in the lower genital tract is a risk factor for clinical chorioamnionitis. They have concluded that genital tract immune hyporesponsiveness permits clinical chorioamnionitis.

Author: Hillier, Sharon L., Caritis, Steve N., Landers, Daniel V., Krohn, Marijane A., Simhan, Hyagriv N., Tejada, Begona Martinez de
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2003
Research and Development in the Physical, Engineering, and Life Sciences, Science & research, Research and Testing Services, Gynecological R&D, Research, Analysis, Causes of, Pregnant women, Inflammation, Risk factors (Health), Cytokines, Obstetrics, Chorioamnionitis, Gynecological research

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Predictive value of the clinical diagnosis of lower genital tract infection in women

Article Abstract:

The evaluation of the current diagnostic approaches to lower genital tract infection in women is discussed. The result shows that specific laboratory testing should be prompted for treatment failures or diagnostic uncertainty.

Author: Hillier, Sharon L., Landers, Daniel V., Krohn, Marijane A., Wiesenfeld, Harold C., Heine, Phillip
Publisher: Elsevier B.V.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2004
Management dynamics, HEALTH SERVICES, Diagnostic Procedures, Medical and Diagnostic Laboratories, Evaluation, Diagnosis, Practice, Laboratory technicians

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Subjects list: Health aspects, Physiological aspects, Care and treatment, United States, Genital diseases, Female, Female genital diseases
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