Vasoactive mediator release by fetal endothelial cells in intrauterine growth restriction and preeclampsia
Article Abstract:
During preeclampsia the fetus produces more cyclic guanosine monophosphate (GMP) to dilate blood vessels and allow blood to flow freely. Preeclampsia is a serious complication of pregnancy. During growth restriction the fetus does not produce cyclic GMP, which could cause blood vessels to constrict.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2001
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Increased nuchal translucency with normal karyotype
Article Abstract:
The association between increased fetal nuchal translucency (NT) thickness in chromosomally normal fetuses and a wide range of fetal malformations, deformations, dysgeneses, and genetic syndromes is reviewed. The vast majority of fetal abnormalities associated with increased nuchal translucency can be diagnosed by a series of investigations that can be completed by 14 weeks of gestation.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2005
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Maternal serum concentration of soluble fms-like tyrosine kinase 1 and vascular endothelial growth factor in women with abnormal uterine artery Doppler and in those with fetal growth restriction
Article Abstract:
A study is conducted to determine whether maternal serum concentration of the angiogenic factor vascular endothelial growth factor (VEGF) and its circulating antagonist, soluble fms-like tyrosine kinase 1 (sFlt-1) are altered in pregnancies that subsequently develop preeclampsia (PE) and in those with established fetal growth restriction (FGR). It is found that maternal serum concentration of sFlt-1 in pregnancies with FGR is increased but is not evident in pregnancies with impaired placentation that subsequently developed either FGR or PE.
Publication Name: American Journal of Obstetrics and Gynecology
Subject: Health
ISSN: 0002-9378
Year: 2006
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