A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer

Article Abstract:

The drug letrozole may lower the risk of cancer recurrence in women who have surgery for breast cancer and also take tamoxifen for up to five years, according to a study of 5,187 women. Seventy-five women who took letrozole had a cancer recurrence after an average follow-up of 2.4 years compared to 132 women who took a placebo, or inactive substance. The four-year disease-free survival rate was 93% in the letrozole group and 87% in the placebo group.

Evaluation, Letrozole

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Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer

Article Abstract:

A study to compare the effectiveness of the drug paclitaxel and the combination paclitaxel plus bevacizumab in the initial treatment for metastatic breast cancer is conduced. Results show that the combination drug extends progression-free survival compared to paclitaxel alone but showed no significant change in the overall survival rate.

United States, Complications and side effects, Dosage and administration, Drug therapy, Combination, Combination drug therapy, Paclitaxel, Clinical report, Bevacizumab

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