A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer
Article Abstract:
The drug letrozole may lower the risk of cancer recurrence in women who have surgery for breast cancer and also take tamoxifen for up to five years, according to a study of 5,187 women. Seventy-five women who took letrozole had a cancer recurrence after an average follow-up of 2.4 years compared to 132 women who took a placebo, or inactive substance. The four-year disease-free survival rate was 93% in the letrozole group and 87% in the placebo group.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2003
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Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
Article Abstract:
A study to compare the effectiveness of the drug paclitaxel and the combination paclitaxel plus bevacizumab in the initial treatment for metastatic breast cancer is conduced. Results show that the combination drug extends progression-free survival compared to paclitaxel alone but showed no significant change in the overall survival rate.
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
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- Abstracts: Cancer in the contralateral breast after radiotherapy for breast cancer. Risk of leukemia after chemotherapy and radiation treatment for breast cancer
- Abstracts: A controlled trial of fluconazole to prevent fungal infections in patients undergoing bone marrow transplantation
- Abstracts: Effects of tamoxifen on cardiovascular risk factors in postmenopausal women. Effects of tamoxifen on bone mineral density in postmenopausal women with breast cancer
- Abstracts: A survey of zidovudine use in pregnant women with human immunodeficiency virus infection. The relationship of pregnancy to human immunodeficiency virus disease progression