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Transmission of human herpesvirus 8 infection from renal-transplant donors to recipients

Article Abstract:

Human herpesvirus 8 (HHV-8) can be transmitted during organ transplantation. This virus has been implicated as a possible cause of Kaposi's sarcoma. Researchers analyzed the development of antibodies to HHV-8 in 220 people who received a kidney transplant. Only six percent were HHV-8-positive at the time of the transplant, but 18% were positive one year later. Within two years of their transplant, two patients who were HHV-8-negative before surgery but HHV-8-positive after surgery developed Kaposi's sarcoma. Further research on six patients revealed that five of the kidney donors tested positive for HHV-8.

Author: Erb, Peter, Thiel, Gilbert, Cathomas, Gieri, Tamm, Michael, Regamey, Nicolas, Wernli, Marion, Witschi, Anne
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 1998
Health aspects, Organ transplant recipients, Disease transmission, Kidneys, Kidney transplantation, Human herpesvirus 8

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Asthma control during the year after bronchial thermoplasty

Article Abstract:

A yearlong randomized, controlled Asthma Intervention Research (AIR) trial examined the efficacy and safety of bronchial thermoplasty as a treatment for moderate or severe persistent asthma. The findings suggested that bronchial thermoplasty in subjects with moderate or severe asthma results in an improvement in asthma control.

Author: Miller, John D., Pavord, Ian D., Cox, Gerard, Thomson, Neil C., Rubin, Adalberto S., Niven, Robert M., Corris, Paul A., Siersted, Hans Christian, Olivenstein, Ronald, McCormack, David, Chaudhuri, Rekha, Laviolette, Michel
Publisher: Massachusetts Medical Society
Publication Name: The New England Journal of Medicine
Subject: Health
ISSN: 0028-4793
Year: 2007
United Kingdom, Care and treatment, Patient outcomes, Prognosis, Asthma, Bronchoconstriction

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