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US military smallpox vaccination program experience

Article Abstract:

A mass smallpox vaccination campaign can be done with few serious adverse effects, according to a study of 450,293 members of the armed forces who were vaccinated between December, 2002 and May, 2003. The most serious adverse effects were encephalitis in one person and heart inflammation in 37. All these persons recovered. There were no cases of virus transmission from healthcare workers who were vaccinated to any patients they may have treated.

Author: Grabenstein, John D., Winkenwerder, William, Jr.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2003
Care and treatment

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Myopericarditis following smallpox vaccination among vaccinia-naive US military personnel

Article Abstract:

Smallpox vaccine may cause a type of heart inflammation called myopericarditis. Among 230,734 military personnel who were vaccinated against smallpox between December, 2002 and March, 2003, 18 developed myopericarditis. This is almost four times higher than the rate in the general population. Smallpox vaccine is based on a live virus that normally causes cowpox.

Author: Gardner, Pierce, Poland, Gregory A., Gibson, Roger L., Gray, Gregory C., Grabenstein, John D., Halsell, Jeffrey S., Riddle, James R., Atwood, J. Edwin, Shope, Robert, Ostroff, Stephen, Eckart, Robert E., Hospenthal, Duane R., Arness, Mark K., Tornberg, David N.
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2003
Causes of, Diseases, Myocarditis, Pericarditis

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Neurologic adverse events associated with smallpox vaccination in the United States, 2002-2004

Article Abstract:

A study aims to determine rates and describe the clinical features of neurologic events associated with smallpox vaccination. During the 2002-2004 smallpox vaccination campaign, reported neurologic events were generally mild and self-limited, and no neurologic syndrome was identified at a rate above baseline estimates.

Author: Chapman, Louisa E., Sejvar, James J., Grabenstein, John D., Iskander, John, Labutta, Robert J., Lane, J. Michael
Publisher: American Medical Association
Publication Name: JAMA, The Journal of the American Medical Association
Subject: Health
ISSN: 0098-7484
Year: 2005
Health aspects, Drug therapy, Smallpox

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Subjects list: United States, Complications and side effects, Soldiers, Smallpox vaccine, Smallpox vaccines
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