Ultrasound evaluation of abnormal umbilical cord coiling in second trimester of gestation in association with adverse pregnancy outcome

Article Abstract:

The antenatal umbilical cord coiling index obtained during fetal anatomic survey in the second trimester is evaluated as a predictor of adverse pregnancy outcome. There exists an association between abnormal umbilical cord coiling detected at the fetal ultrasound anatomic survey in the second trimester and a higher prevalence of small for gestational age neonates and nonreassuring fetal status in labor.

Author: Chervenak, Frank A., Chasen, Stephen T., Perni, Sriram C., Predanic, Mladen, Baergen, Rebecca N.
Fetal blood

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Patient preference regarding first-trimester aneuploidy risk assessment

Article Abstract:

Patients views regarding disclosure of first-trimester Down syndrome risk assessment results compared with withholding results until a single, more accurate second-trimester screening result is available, was assessed. Older patients and those patients with a better understanding of screening tests preferred immediate disclosure of first-trimester risk assessment results.

Author: Chervenak, Frank A., Chasen, Stephen T., Sharma, Geeta, Gold, Heather T., McCullough, Laurence, Alt, Abigail K.
Aneuploidy

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Does a "vanishing twin" affect first-trimester biochemistry in Down syndrome risk assessment?

Article Abstract:

The impact of spontaneous reduction in multifetal pregnancy on first-trimester maternal serum biochemistry is evaluated. It is shown that recent spontaneous reduction is associated with higher values of plasma protein-A (PAPP-A) and free beta-hCG and these differences have the potential to affect risk assessment for fetal aneuploidy.

Author: Chervenak, Frank A., Kalish, Robin B., Perni, Sriram C., Predanic, Mladen, Chasen, StephenT.
Risk factors, Disease/Disorder overview

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Subjects list: Research, United States, Pregnancy, Complications of, Pregnancy complications, Diagnosis, Down syndrome
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