Pulmonary amyloidosis: the Mayo Clinic experience from 1980 to 1993
Patients with amyloid throughout their body seem to have the poorest survival rates as compared to other classifications of amyloidosis. Amyloid is an abnormal accumulation of fibrous protein in vital tissues and organs of the body. Researchers presented characteristics of 55 patients with amyloidosis in the lungs and airways seen over a 13-year period. These patients had various types of amyloidosis including primary, secondary, and hereditary system-wide amyloidosis, amyloidosis limited to the airways, amyloid nodules, and senile amyloidosis. Patients with system-wide amyloidosis had a median survival of 16 months following identification of the disease. Three patients with amyloidosis limited to the lungs and airways required laser therapy to open blocked airways. Doctors safely removed lung tissue samples used to identify amyloid disease from 11 patients with minimal blood loss.
Publication Name: Annals of Internal Medicine
Chicago clinic begins inoculations in Phase III AIDSVAX trial
Volunteers have begun receiving inoculations in the North American trial of AIDSVAX, the first vaccine against HIV to undergo Phase III clinical trials. The trial is being conducted by the Chicago Center for Clinical Research, one of the first participants in the study sponsored by AIDSVAX developer VaxGen Inc of South San Francisco, CA. Inoculations are being administered to volunteers at risk for HIV infection through sexual transmission but are currently unaffected, primarily gay men and women with HIV-infected partners.
Publication Name: Vaccine Weekly
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