Does the p53 up-regulated Gadd45 protein have a role in excision repair?

Article Abstract:

Excision repair in DNA could not be stimulated by Gadd45 protein. This result indicates that Gadd45 does not have any effect on the activity of human excision nuclease or on the repair synthesis step of human nucleotide excision repair.

Author: Wood, Richard D., Fornace, Albert J., Jr., Smith, Martin L., Hall, Peter A., Sancar, Aziz, Shivji, Mahmud K.K., Kazantsev, Aleksey, Kearsey, Jonathan M., Chen, I-T
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1995
DNA repair, Biochemical genetics

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Role of Mouse Cryptochrome Blue-Light Photoreceptor in Circadian Photoresponses

Article Abstract:

Research on the biological processes are conducted by scientists and their findings are presented. The circadian rhythms are analyzed with tests performed on mice. The details of these processes and the subsequent results are discussed.

Author: Takahashi, Joseph S., Smithies, Oliver, Sancar, Aziz, Kazantsev, Aleksey, Vitaterna, Martha Hotz, Thresher, Randy J., Miyamoto, Yasuhide, Hsu, David S., Petit, Claude, Selby, Christopher P., Dawut, Lale
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1998
Mice, Mice (Rodents), Circadian rhythms

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No "end of history" for photolyases

Article Abstract:

Photoreactivation is the mechanism through which cells repair UV damage. The mechanism involves the enzyme photolyase. Now scientists have discovered a new photolyase specific for (6-4) photoproduct in Drosophila.

Author: Sancar, Aziz
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1996
Analysis, Enzymes, Photochemical research, Enzyme structure-activity relationships

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Subjects list: Research
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