Sex and Repression

Article Abstract:

A recent discovery that subunits of a large protein complex are related to the mitotic chromosome condensation and segregation machinery surprised researchers. The subunits are required for dosage compensation in nematodes, a mechanism of transcriptional repression that occurs in hermaphrodites. The next phase of this research will likely involve understanding a way in which this chromosome-wide recognition has evolved.

Author: Kelley, Richard L., Kuroda, Mitzi I.
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1999
Sex chromosomes, Sex chromosome abnormalities

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X chromosome dosage compensation in Drosophila

Article Abstract:

Differing interpretations of C chromosome dosage compensation in Drosophila depend on whether the major defect in mls mutant males is too little X-encoded gene products or too much autosomally encoded products. Views on both sides of the controversy are presented.

Author: Kelley, Richard L., Kuroda, Mitzi I., Birchler, James A.
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1996
Genetic aspects, Drosophila, X chromosome, Dosage compensation (Genetics)

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Promiscuous chromosomal proteins: complexes about sex

Article Abstract:

Researchers have found a mechanistic link between chromosome segregation in meiosis and chromosome-dependent regulation of genes. Their work provides information about how chromosome structure affects function.

Author: Villeneuve, Anne M., Kuroda, Mitzi I.
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1996
Physiological aspects, Meiosis, Chromosomal proteins

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Subjects list: Research, Chromosomes
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