Cognitive deterioration in Alzheimer's disease: behavioral and health factors

Article Abstract:

People with Alzheimer's disease lose their ability to know, think, learn and judge (cognitive ability) over a period of time. Not much is known about the factors that influence cognitive decline or the usual rate of decline. In fact, the rate of decline is quite variable, but those with certain health or behavior problems have a cognitive decline rate of about one and one-half to five times faster than those who do not. Those who previously or currently abuse alcohol, those with other neurological disease, and those who are agitated have the most rapid rates of decline. (Consumer Summary produced by Reliance Medical Information, Inc.)

Physiological aspects, Nervous system

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Effect of vascular lesions on cognition in AlzheimerEs diseases: a community-based study

Article Abstract:

A study was conducted to investigate whether clinical and neuropathological differences exist between AlzheimerEs disease (AD) cases with and without vascular lesions neuropathologically diagnosed using consortium to establish a registry for AlzheimerEs disease (CERAD) criteria. The results showed that Ad/V cases had less severe AD pathology than those with AD alone, indicating that cerebrovascular disease likely contributes to the severity of cognitive impairment in those with AD.

United States, Health aspects, Blood circulation disorders, Vascular diseases

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Cognitive decline in Alzheimer's disease: a longitudinal investigation of risk factors for accelerated decline

Article Abstract:

Mini-mental state examination and other statistical techniques help assess the variations in cognitive function with Alzheimer's disease. Multivariate regression analysis reveals the influence of demographic characteristics, health problems and behavioral problems on the decline in cognitive function. This decline further depends on age, higher education and agitation at intake.

Research, Analysis, Demography, Cognitive balance

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