Episodic remembering in a population-based sample of nonagenarians: does major depression exacerbate the memory deficits seen in Alzheimer's disease?
Article Abstract:
Major depression (MD) has little deteriorative effect on episodic memory in very old adults with Alzheimer's disease (AD). Very old adults with MD show little difference from normals in their performance on face recognition, word recall and object recall. Although subjects with AD poorly perform on all task variables of long-term episodic memory, the coexistence of MD has little deteriorating effect on the performance. The coexistence of MD also show little adverse effect on short-term memory. Performance-related difference between MD subjects without AD and normals is negligible.
Publication Name: Psychology and Aging
Subject: Seniors
ISSN: 0882-7974
Year: 1996
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Influences of cognitive support on episodic remembering: tracing the process of loss from normal aging to Alzheimer's disease
Article Abstract:
Research was conducted on the episodic task performance among normal older adults, early incident Alzheimer's disease (AD) patients and prevalent AD patients during a three-year interval. The objectives of the research were to evaluate the cognitive support utilization pattern and the primary and secondary memory status in preclinical and clinical AD. Results revealed observations of episodic memory task deficits among patients who developed AD several years prior to diagnosis. The incident AD patients degenerated faster than the normal older adults.
Publication Name: Psychology and Aging
Subject: Seniors
ISSN: 0882-7974
Year: 1998
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Three-year changes in cognitive performance as a function of apolipoprotein E genotype: evidence from very old adults without dementia
Article Abstract:
Apolipoprotein E (epsilon)4 may not affect cognitive performance in adults without dementia. When it does influence cognitive performance, such may be related to impending dementia rather than to the effect of the genotype on cognition in normal aging. This was gleaned from a study of whether baseline cognitive performance and three-year longitudinal changes were influenced by apolipoprotein E (epsilon)4 status. Of specific focus were cognitive abilities that include memory, visuospatial functioning and verbal fluency.
Publication Name: Psychology and Aging
Subject: Seniors
ISSN: 0882-7974
Year: 1998
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