Long-term caloric restriction improves baroreflex sensitivity in aging Fischer 344 rats
Article Abstract:
Baroreflex sensitivity, mean arterial pressure (MAP) and heart rate were compared in younger and older rats with free or calorie restricted diets to identify whether calorie restriction would reduce age-associated declines in cardiovascular function. Diet had no effect on MAP in younger rats; younger rats and ad libitum fed older rats had higher MAP that calorie restricted older rats. Heart rate was lower for calorie restricted rats regardless of age. Aging reduced reflex responsiveness, and calorie restriction increased reflex responsiveness, to nitroprusside injections.
Publication Name: Journals of Gerontology
Subject: Seniors
ISSN: 0022-1422
Year: 1993
User Contributions:
Comment about this article or add new information about this topic:
The effects of prenatal alcohol exposure on the behavior of rats during their life span
Article Abstract:
The effects of prenatal alcohol exposure on adaptive performance in rats increase with age and are most noticeable during the senile phase of life, when adaptability is at its lowest point. Rats with moderate alcohol-induced prenatal damage were compared to controls at juvenile (zero-three months), adult (three-27 months) and senile (over 27 months) stages for reflex and locomotor ability, coordination, cognitive ability and adaptation to atmospheric and pharmacological stresses. No substantial differences were found at the juvenile stage in most areas tested.
Publication Name: Journals of Gerontology
Subject: Seniors
ISSN: 0022-1422
Year: 1993
User Contributions:
Comment about this article or add new information about this topic:
Effects of dietary protein restriction on nitrogen balance and cardiovascular functions in aged rats
Article Abstract:
Age-related changes in protein metabolism, such as nitrogen loss, may contribute to disease and physiological function losses. To test this hypothesis young (six-seven month) and old (24-25 month) rats were fed either a 12% or a 23% protein diet and measured for nitrogen balance and cardiovascular health. The low-protein group of older rats had positive nitrogen balance and the other group had a negative balance. Endothelium-dependent aortic relaxation was less in the low-protein rats. as were age-associated increases in platelet aggregation.
Publication Name: Journals of Gerontology
Subject: Seniors
ISSN: 0022-1422
Year: 1993
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Long-term dietary restriction in older-aged rhesus monkeys: effects on insulin resistance. Commentary on "Effect of Long-term Caloric Restriction on GLUT4, Phosphatidylinositol-3 Kinase p85 Subunit, and Insulin Receptor Substrate-1 Protein Levels in Rhesus Monkey Skeletal Muscle"
- Abstracts: Commentary on "Long-term Calorie Restriction Reduces Energy Expenditure in Aging Monkeys.". Commentary on "Age-Dependent Increase in Infarct Volume Following Photochemically Induced Cerebral Infarction: Putative Role of Astroglia."
- Abstracts: Transdermal estradiol with oral progestin: biological and clinical effects in younger and older postmenopausal women
- Abstracts: Transdermal estradiol with oral progestin: biological and clinical effects in younger and older postmenopausal women. part 2
- Abstracts: Tom Meyer lures them back; his homes are for the (blue) birds. Color me blue: why today's crayons are a pale reminder of better days