Chronic fatigue syndrome: Exercise performance related to immune dysfunction

Article Abstract:

A cross-sectional study examines the interactions between several intracellular immune variables and exercise performance in patients with chronic fatigue syndrome (CFS). The results provide preliminary evidence of an association between RNase L proteolysis and exercise in CFS patients, indicating an association between intracellular immune deregulation and exercise performance in CFS patients.

Analysis, Proteolysis, Chronic fatigue syndrome

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AMP-activated protein kinase: A key system mediating metabolic responses to exercise

Article Abstract:

A study was conducted to understand the structure and regulation of AMP activated protein kinase (AMPK), activation of AMPK during muscle contraction and also to identify which metabolic responses to exercises are mediated by AMPK activation. The activation of AMPK is responsible for many of the acute metabolic changes that occur in muscle during exercise or contraction.

Influence, Metabolism, Muscle contraction

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Interaction between the AMP-activated protein kinase and mTOR signaling pathways

Article Abstract:

The AMP-activated protein kinase (AMPK) is regulated by both AMP and ATP where the binding of AMP to AMPK allows it to be phosphorylated by upstream kinases, resulting in its activation. It is found that the activation of AMPK results in decreased mTOR signaling and inhibition of protein synthesis.

Protein synthesis, Protein biosynthesis, Rapamycin

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