A nanomechanical device based on the B-Z transition of DNA

Article Abstract:

Branched motifs of DNA can provide components to assemble nanoscale objects, links and arrays. It is shown than they can also act as the base for dynamic assemblies. A supramolecular device was constructed, comprising two rigid DNA double-crossover (DX) molecules. The transition between the B and Z forms of DNA are used to effect switchable motion. Fluorescence resonance energy transfer spectroscopy is used to detect relative repositioning.

Author: Seeman, Nadrian C., Mao, Changde, sun, Weiqiong, Shen, Zhiyong
Molecules

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Assembly of Borromean rings from DNA

Article Abstract:

The assembly of Borromean rings from single-stranded DNA could be achieved by identifying the positive and negative crossings or unit tangles then linking them into branched junctions and connecting them via the recognition-directed ligation. This construction method could be used as a guide in the formation of target topological products from other polymers.

Author: Mao, Chengde, Seeman, Nadrian C., Sun, Weiqiong
Analysis

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Logical computation using algorithmic self-assembly of DNA triple-crossover molecules

Article Abstract:

The method of self-assembling DNA-based Wang tiles is demonstrated being used to carry out DNA-based computing. The system can perform four steps of a logical operation that can be used as a basis for a theoretically unbreakable cryptosystem.

Author: Mao, Chengde, LaBean, Thomas H., Reif, John H., Seeman, Nadrian C.
Molecular computing

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Subjects list: Research, DNA
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