A positive feedback mechanism governs the polarity and motion of motile cilia

Article Abstract:

The developmental mechanisms that polarize cilia are analyzed by using the ciliated cells in the developing Xenopus larval skin as a model system. The results have shown that during refinement, fluid flow required for determining cilia polarity, thus revealing a novel mechanism in which tissue patterning coupled with fluid flow act in a positive feedback loop to direct the planar polarity cilia.

Developmental biology, Cells, Xenopus, Cell motility, Cilia and ciliary motion, Cilia

---

Insulin disrupts beta-adrenergic signaling to protein kinase A in adipocytes

Article Abstract:

A study is conducted to show that in adipocytes, chronically high insulin levels inhibit beta-adrenergic receptors from activating protein kinase A (PKA). Chronically high insulin levels may disrupt the close apposition of beta-adrenergic receptors and PKA, identifying a new mechanism for crosstalk between heterologous signal transduction pathways.

Protein kinases, Fat cells, Adipocytes, Beta adrenoceptors, Adrenergic beta receptors

---

Visualizing the mechanical activation of Src

Article Abstract:

A genetically encoded Src reporter that enables the imaging and quantification of spatio-temporal activation of Src in live cells using fluorescent resonance energy transfer (FRET). A rapid distal Src activation along the plasma membrane using the Src reporter is observed.

Cell membranes, Structure, Energy transformation

Similar abstracts:

• Abstracts: A critical ligamentous mechanism in the evolution of avian flight. Beyond the bones
• Abstracts: Function and mechanism of mirror-image ambiguity in bumblebees. How do bumblebees first find flowers? Unlearned approach responses and habituation
• Abstracts: When will we tame the oceans? One of a kind
• Abstracts: PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates. Class 3 semaphorins control vascular morphonogenesis by inhibiting integrin function
• Abstracts: A tunable carbon nanotube electromechanical oscillator. Systematic design of chemical oscillators using complexation and precipitation equilibria

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.