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Zoology and wildlife conservation

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Abstracts » Zoology and wildlife conservation

CDK-dependent phosphorylation of BRCA2 as a regulatory mechanism for recombinational repair

Article Abstract:

The carboxy-terminal region of BRCA2, which interacts directly with the essential recombination protein RAD51, contains a site that is phosphorylated by cyclin-dependent kinanses is reported. The results indicate that S3291 phosphorylation might provide a molecular switch to regulate RAD51 recombination activity, providing new insight into why BRCA2 C-terminal deletions lead to radiation sensitivity and cancer predisposition.

Author: Jasin, Maria, West, Stephen C., Hunt, R. Timothy, Esashi, Fumiko, Christ, Nicole, Gannon, Julian, Liu, Yilun
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005

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Photosystem II core phosphorylation and photosynthetic acclimation require two different protein kinases

Article Abstract:

A second protein kinase, STN8, is required for the quantitative phosphorylation of photosystem II (PSII) core proteins for the plant Arabidopsis. The phosphorylation of light-harvesting (LHCII) proteins, or of an unknown substrate of STN7, is very important for the control of photosynthetic gene expression.

Author: Becker, Thomas, Bonardi, Vera, Pesaresi, Paolo, Wagner, Raik, Jahns, Peter, Schleiff, Enrico, Pfannschmidt, Thomas, Leister, Dario
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
Gene expression, Arabidopsis

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Subjects list: Research, United States, Protein kinases, Phosphorylation
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