Multiple transport modes of the cardiac Na (super +1)/Ca (super 2+) exchanger

Article Abstract:

The cardiac Na (super +1)/Ca (super2+) exchanger (NCX1) is a bi-directional Ca (super 2+) transporter that contributes to the electrical activity of the heart. It is shown, using an ion-selective electrode technique to quantify ion fluxes in giant patches, that ion flux ratios are approximately 3.2 for maximal transport in either direction.

United States, All Other Miscellaneous General Purpose Machinery Manufacturing, Ion Exchange Membranes, General industrial machinery, not elsewhere classified, Ion-permeable membranes

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The molecular architecture of the nuclear pore complex

Article Abstract:

The molecular architecture of the yeast, Saccharomyces cerevisiae nuclear pore complexes (NPC) were determined from a collection of biophysical and proteomic data. The structure of NPC was found to be made up of a core scaffold, which is structurally analogous to vesicle-coating complexes.

Physiological aspects, Saccharomyces, Nuclear membranes, Nuclear membrane, Structure

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Coat control by curvature

Article Abstract:

Dynamics of assembly and disassembly of protein coat of spherical vesicles that mediate transportation of substances in cells are described. The self-regulating mechanism for vesicle formation and role of Arf1 protein in coatmer (COPI)- type coat is investigated.

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