When giants roamed

Article Abstract:

A demonstration that the passage of Jupiter and Saturn through a 1:2 mean-motion resonance (MMR) could account for the orbital spacing, eccentricities and inclinations of all four giant planets are presented. An MMR is a 'sweet spot' in the Solar System when the orbital periods of two bodies are ratios of whole numbers, and this is also a site where a planet's periodic gravitational perturbation can 'pump-up' another body's eccentricity and/or inclination.

Outer space, Orbits (Astrophysics), Orbits

---

Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3

Article Abstract:

The durability of phosphatidylinositol-3-OH kinase (PI(3)K)/Akt inhibition by human epidermal growth factor receptor (HER)-family tyrosine kinase inhibitors (TKIs) is investigated. The analysis has shown that HER3 and PI(3)K/Akt signalling is not effectively inhibited by current TKIs and hence HER3 transphosphorylation might be a better biological marker of efficacy to guide future therapies.

Physiological aspects, Tyrosine, Phosphotransferases, Epidermal growth factor receptors

---

Similar abstracts:

• Abstracts: Scientists close in on 'cell from hell' lurking in Chesapeake Bay
• Abstracts: The big match. Early gas stripping as the origin of the darkest galaxies in the universe
• Abstracts: The evolution of life-sciences sales. A Plio-Pleistocene hominid from Dmanisi, East Georgia, Caucasus
• Abstracts: Keys to capacity. High-tech cluster bombs: why successful biotech hubs are the exception, not the rule
• Abstracts: The iceman of Svalbard. Seismic identification of along-axis hydrothermal flow on the East Pacific Rise

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.