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A 700 bp cis-acting region controls mating-type dependent recombination along the entire left arm of yeast chromosome III

Article Abstract:

Donor preference of Saccharomyces cerevisiae mating-type MATa gene requires the activation of the donor on the left arm of the chromosome which includes HML alpha and HMR alpha. The activation of the chromosomal region of MATa gene is enhanced by the orientation-independent 700 bp cis-acting region. The recombinant enhancer also improves the accessibility of the deoxyribonucleic acid by altering the structure of the chromosomes of the MATa gene.

Author: Haber, James E., Wu, XiaoHua
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1996
Gene expression, Saccharomyces, Chromosomes, Recombinant proteins

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Srs2 and Sgs1-Top3 suppress crossovers during double-strand break repair in yeast

Article Abstract:

Research describes factors that regulate the crossover outcomes during gene conversion during mitosis using ectopic homologous recombination assay. Results reveal two kinetically different double-strand breaks repair processess, one leading to noncrossovers and the other to both crossovers and noncrossovers. Data indicate that both Sgs1 and Srs2 suppress crossing-over in budding yeast.

Author: Malkova, Anna, Haber, James E., Liberi, Giordano, Foiani, Marco, Ira, Grzegorz
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2003
Italy, Science & research, Research, Physiological aspects, DNA repair, Mitosis, Crossing over (Genetics)

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The fuss about Mus81

Article Abstract:

Research findings suggest that Mus81 protein possesses many of the properties of Holliday junctions such as endonucleolytic cleavage during DNA recombination and replication. Data indicate that Mus81 protein associates with the recombinat protein Rad54 and interacts with meiotic paralog Rad53.

Author: Haber, James E., Heyer, Wolf-Dietrich
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2001
United States, DNA, Yeast, Yeast (Food product), Meiosis

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Subjects list: Analysis, Genetic aspects, Genetic recombination
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