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Individual DNA bands obtained by RAPD analysis of canine genomic DNA often contain multiple DNA sequences

Article Abstract:

A study was conducted to analyze DNA bands of dogs determined by the random amplified polymorphic DNA (RAPD) technique. A DNA template isolated from miniature poodles was utilized to carry out RAPD-polymerase chain reaction. Positive clones were then examined by restriction digestion. Experimental results indicated that RAPD bands amplified from the canine genome support more than one DNA fragment.

Author: Aguirre, G.D., Ray, K., Gu, W., Post, C.M.
Publisher: Oxford University Press
Publication Name: The Journal of Heredity
Subject: Biological sciences
ISSN: 0022-1503
Year: 1999
Research, Analysis, DNA, Genomes, Chromosome mapping

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Comparative mapping of the DiGeorge region in the dog and exclusion of linkage to inherited canine conotruncal heart defects

Article Abstract:

Deletions and other rearrangements in the human chromosome 22q11 area lead to DiGeorge syndrome (DGS), with conotruncal heart defects (CTDs) a frequent component. Physical and linkage maps of the canine homolog of the Di-George region were constructed and the question of linkage of CTD to canine genes was examined.

Author: Patterson, D.F., Werner, P., Raducha, M.G., Prociuk, U., Henthorn, P.S., Budarf, M.
Publisher: Oxford University Press
Publication Name: The Journal of Heredity
Subject: Biological sciences
ISSN: 0022-1503
Year: 1999
Abnormalities, Heart, Cardiovascular abnormalities

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Subjects list: Genetic aspects, Dogs
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