Polycomb and trithorax group proteins mediate the function of a chromatin insulator

Article Abstract:

Research was conducted to test whether mod(mdg4) proteins display the properties of a trithorax gene. The Mod(mdg4) protein was prepared in Escherichia coli as a fusion protein while Western analysis was carried out by standard procedures. Results indicated a link between the mechanisms of insulator function and the molecular bases by which polycomb and trxG proteins influence gene expression. They also showed that boundary elements interfered with the normal communication between enhancers and promoters.

Gene expression

---

TRF2 protects human telomeres from end-to-end fusions

Article Abstract:

Research was conducted to test whether the human telomeric protein TRF2 plays an important role in the protective activity of telomerases. the cDNA encoding full-length TRF2 was prepared under tetracyclin-controlled promoter while the cells were washed with cold phosphate-buffered saline. Results indicated the involvement of TRF2 in the main functions associated with telomerases in somatic human cells. They also showed that TRF2 helps maintain the correct structure at telomere termini.

Telomeres

---

Similar abstracts:

• Abstracts: A hot topic: the origin of hyperthermophiles. Integrin activation by R-ras. Septin scaffolds and cleavage planes in Saccharomyces
• Abstracts: Cell adhesion: the molecular basis of tissue architecture and morphogenesis. The molecules of mammalian fertilization
• Abstracts: Polymerases and the replisome: machines within machines. IAP family proteins - suppressors of apoptosis
• Abstracts: Bayesian procedures for the estimation of mutation rates from fluctuation experiments. Lancelot Hogben, 1895-1975
• Abstracts: Morphometry of the digestive tracts of some passerine birds. part 2 A new species of extinct flightless passerine (Emberizidae: Emberiza) from the Canary Islands

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.