A marker set for construction of a genetic map of the silver fox (Vulpes vulpes)

Article Abstract:

The genomic organizations genomic organizations of the silver fox (Vulpes vulpes) and the dog (Canis familiaris) are compared. Several single nucleotide polymorphisms (SNPs) are found when a sequence comparison of genes from tame and aggressive foxes is conducted. Canine genomic tools are utilized in developing a fox meiotic map and mapping behavioral traits in the fox due to a close relationship between the fox and dog.

Behavior, Dogs, Red fox, Genomics

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Feline adult beta-globin polymorphism reflected in restriction fragment length patterns

Article Abstract:

A study was conducted to analyze the molecular basis of feline adult beta-globin polymorphism reflected in restriction fragment length patterns. Southern blot analysis was carried out on the beta-globin gene region from 25 cats with 13 different high-performance liquid chromatography patterns. Results indicated an autosomal codominant mode of inheritance of the beta-globin chains with seven haplotypes.

Globin genes, Domestic animals

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Inheritance, Biochemical Abnormalities, and Clinical Features of Feline Mucolipidosis II: The First Animal Model of Human I-Cell Disease

Article Abstract:

A domestic shorthair cat population was used to develop an animal model for the human lysosomal storage disease Mucolipidosis II, or I-cell disease, to use in therapeutic intervention and pathogenesis research. Mode of inheritance, lysosomal enzyme activities, and radiographic and clinical features were found to be homologous with I-cell disease in humans.

Usage, Physiological aspects, Diseases, Animal models in research, Animal research models, Mucolipidoses

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