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Metastatic tumor antigen 3 is a direct corepressor of the Wnt4 pathway

Article Abstract:

The effect of targeted overexpression of metastatic tumor antigen (MTA3) in mouse mammary gland was investigated in order to better understand MTA3's biological functions in physiological settings. It was found that Wnt4 is a direct target of MTA3 and that phenotypic changes in the MTA3 transgenic mammary glands remarkably resemble those from the Wnt4-null mice.

Author: Hao Zhang, Kumar, Rakesh, Talukder, Amjad H.
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2006
Genetic aspects, Metastasis, Cancer metastasis, Tumor antigens, Tumour antigens

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What better measure than ribosome synthesis?

Article Abstract:

The control of cell growth involves control of ribosome synthesis. The cell somehow matches the replication of its genome, with the implicit decision to divide, or perhaps to its predicted size at the time division occurs.

Author: Rudra, Dipayan, Warner, Jonathan, R.
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2004
RNA, Ribosomes, RNA synthesis

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