Beadex encodes an LMO protein that regulates Apterous LIM-homeodomain activity in Drosophila wing development: a model for LMO oncogene function
Article Abstract:
LIM-homeodomain protein Apterous (AP) activity is essential to formation of the dorsal-ventral axis of the wing in Drosophila. The Ap activity levels are modulated by dLMO,a protein, which is encoded by the Beadex (Bx) gene. The dominant interference mechanism of dLMO action may be a suitable model for the way LMO oncogenes bring on leukemia and lymphoma when they are misexpressed in T cells.
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 1998
Observations, Gene expression, Cell differentiation, Wings (Animal), Animal wings, Oncogenes
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 1998
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MicroRNA miR-14 acts to modulate a positive autoregulatory loop controlling steroid hormone signaling in 'Drosophila'
Article Abstract:
The microRNA miR-14 modulates a positive autoregulatory loop by limiting the Drosophila Ecdysone receptor (EcR) gene.
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2007
Science & research, Medicinal and Botanical Manufacturing, Medicinals and botanicals, Steroids, RNA, Steroid hormones, Ecdysone, Report
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2007
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Subjects list: Research, Genetic aspects, Drosophila
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