Capping protein levels influence actin assembly and cell motility in dictyostelium

Article Abstract:

Dictyostelium cells with altered levels of capping protein, which caps barbed ends of filaments, were examined to determine the role of the protein in actin assembly in vitro. It was shown that capping protein limits actin polymerization by preventing the loss and addition of monomers. Increased level of capping protein increased the rate of cell movement, suggesting that capping protein induces changes in cell motility. As a result, overexpressing cell lines exhibited faster motility than underexpressed lines.

Cells, Actin, Cell migration, Dictyostelium

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Bacterial motility and signal transduction

Article Abstract:

The second meeting on Bacterial Locomotion and Signal Transduction saw 180 researchers discuss their developments, particularly at the molecular level. Most of the research is summarized, including those regarding chemoreceptors, signaling circuitry, the response regulator CheY, signaling components of other organisms, bacterial flagella, myxobacteria, crosstalk and integrated regulation, and tactic behavior in an archaebacterium. Trends of increasing relevance are also discussed.

Conferences, meetings and seminars, Bacteria, Cellular signal transduction, Bacterial motility

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Ephrin-B2 controls cell motility and adhesion during blood-vessel-wall assembly

Article Abstract:

Study is conducted to show that mural cells require ephrin-B2, a ligand for Eph receptor tyrosine kinases, for normal association with small-diameter blood vessels. Results indicate that the role of ephrin-B2 and EphB receptors in these processes involves Crk-p130 (CAS) signaling and suggest that ephrin-B2 has some cell-cell-contact-independent functions.

United States, Science & research, Blood vessels, Tyrosine, Adhesion, Adhesion (Surface chemistry), Chemical properties

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