Gene switching and the stability of odorant receptor gene choice

Article Abstract:

A genetic strategy is devised that allows examining the stability of receptor expression. It is observed that the majority of neurons that have chosen a specific receptor continue to express this receptor for the life of the cell, however, a subpopulation of cells switches receptor gene choice. These observations suggest a mechanism of olfactory receptor (OR) gene choice in which a cell selects only one receptor allele but can switch at low frequency.

Science & research, Research, Gene expression

---

Science imitates art: the cloning of mice from olfactory sensory neurons

Article Abstract:

An oldfactory sensory neurons functional identity is defined by its expression of one odorant receptor from large multigene family. The complexity of this process has led to speculation that DNA rearrangements limit the expression of one receptor gene per cell.

Biological Product (except Diagnostic) Manufacturing, Drugs, DNA Clones, Analysis, Sensory receptors

---

Similar abstracts:

• Abstracts: Coding of olfactory information: topography of odorant receptor expression in the catfish olfactory epithelium

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.