Control of MAP kinase signaling specificity or how not to go HOG wild

Article Abstract:

Mitogen-activated protein kinase (MAPK) cascades are central to many signal transduction pathways in eukaryotic cells. Studies of yeast cells have given new information. The cascades in yeast cells number five, of which two control response to solute concentration. One of those is the HOG pathway that orchestrates response to high osmolarity. More sharing of components for the mating filamentation and HOG pathways exists than had been previously thought. MAP kinases can serve as specificity factors.

Genetic aspects, Genetic regulation, Yeast, Yeast (Food product), Protein kinases, Mitogens, Cell physiology, Cytoplasmic filaments

---

Synaptonemal complex morphogenesis and sister-chromatid cohesion require Mek1-dependent phosphorylation of a meiotic chromosomal protein

Article Abstract:

Yeast meiotic chromosome core development into full-length synaptonemal complexes must have the MED1 gene product which is a protein kinase homolog that is meiosis-specific. Fluorescent in situ hybridization analysis gives results that show that it is likely that Mek1-mediated phosphorylation of the Red1 protein is needed for meitoic sister-chromatid cohesion. Thus there is a possibility that cohesion is regulated by protein phosphorylation.

United States, Morphogenesis, Phosphorylation, Chromosomes, Meiosis

---

Similar abstracts:

• Abstracts: Insulin-like signaling and the neural circuit for integrative behavior in C. elegans. The UNC-73/Trio RhoGEF-2 domain is required in separate isoforms for the regulation of pharnyx pumping and normal neurotransmission in C. elegans
• Abstracts: 14-3-3 proteins are essential for RAS/MAPK cascade signaling during pseudohyphal development in S. cerevisiae
• Abstracts: Interaction of Agouti protein with the melanocortin 1 receptor in vitro and in vivo. Pointing roots in the right direction: the role of auxin transport in response to gravity
• Abstracts: Cell cycle control of chorion gene amplification. Functional and regulatory interactions between Hox and extradenticle genes
• Abstracts: A new NEDD8-ligating system for cullin-4A. Asymmetric cell division: from A to Z

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.