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Coupled positive and negative feedback circuits form an essential building block of cellular signaling pathways

Article Abstract:

The role of positive and negative feedback loops are explored to understand the complex regulatory mechanism of cellular signaling systems caused by feedback loops. The coupled feedback loops have enabled cellular systems to produce perfect responses to noisy stimuli with respect to signal duration and amplitude, suggesting that the coupled positive and negative feedback loops form essential signal transduction motifs in cellular signaling systems.

Author: Kwang-Hyun Cho, Dongsan Kim, Yung-Keun Kwon
Publisher: John Wiley & Sons, Inc.
Publication Name: BioEssays
Subject: Biological sciences
ISSN: 0265-9247
Year: 2007
Cellular signal transduction, Cell physiology

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Apoptosis--an introduction

Article Abstract:

This review discusses apoptosis or programmed cell death with reference to genetic regulation, role played by BcI-2 proteins, caspases, receptor-mediated apoptosis, apoptosis and proliferation, intrinsic pathway, and phagocytosis of apoptotic bodies.

Author: Lawen, Alfons
Publisher: John Wiley & Sons, Inc.
Publication Name: BioEssays
Subject: Biological sciences
ISSN: 0265-9247
Year: 2003
Australia, Physiological aspects, Cell death, Genetic regulation, Phagocytosis, Apoptosis

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Subjects list: Research, Cellular control mechanisms, Cell regulation
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