Elevated shear stress protects Escherichia coli cells adhering to surfaces via catch bonds from detachment by soluble inhibitors

Article Abstract:

A study conducted discovered that when catch bonds, whose bond life increases with increased life force, shear stress may dramatically increase the ability of bacteria to withstand detachment by soluble competitive inhibitors. Shear stress-enhanced reduction of bacterial detachment having major physiological and therapeutic implications and needs to be considered when developing and screening drugs.

HEALTH SERVICES, All Other Miscellaneous Ambulatory Health Care Services, Disease Testing Programs, Analysis, Drugs, Drug evaluation

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Chaperone Hsp31 contributes to acid resistance in stationary-phase Escherichia coli

Article Abstract:

A study was conducted to show that Hsp31 plays an important role in the acid resistance of starved Escherichia coli but has little influence on oxidative-stress survival. The findings suggest that Hsp31 did not play any significant role in the management of oxidative damage but helps the cells to handle combination of oxidative and thermal stress.

Genetic aspects

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Escherichia coli K1's capsule is a barrier to bacteriophage T7

Article Abstract:

The expression of the K1 capsule in Escherichia coli physically blocks infection by T7, a phage that recognizes lipopolysaccharide as the primary receptor. It suggests that the capsule plays an important role as a defense against some phages that recognize structures beneath it and the K1-specific phages evolved to counter this physical barrier.

Prevention, Bacteriophages, Microbial polysaccharides

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