Elongation of the Kcnq1ot1 transcript is required for genomic imprinting of neighboring genes

Article Abstract:

A differentially methylated CpG island, KvDMR is contained in the imprinted gene cluster at the telomeric end of mouse chromosome 7, which is required for the imprinting of multiple genes and it maps within intron 10 of Kcnq1 contains the promoter for a paternally expressed, noncoding, antisense transcript Kcnq1ot1. The Kcnq1ot1 transcript was truncated by inserting a transcriptional stop signal downstream of the promoter.

Genomic imprinting

---

Cotranscriptional recruitment of the dosage compensation complex to X-linked target genes

Article Abstract:

The study provides direct evidence for transcription-dependent recruitment of the male-specific lethal (MSL) complex to X-linked genes. Results support a model for MSL complex targeting to transcriptionally active X-linked genes that encode a certain combination of small degenerative target sequences in their transcribed region.

Genetic code

---

The notch target genes Hey1 and Hey2 are required for embryonic vascular development

Article Abstract:

Direct targets of notch signaling are the Hey family of bHLH transcription factors. Hey1/Hey 2 are important transducers of notch signals for cardiovascular development that can mediate arterial cell fate decisions.

Electronic components, not elsewhere classified, Other Electronic Component Manufacturing, Transducers

Similar abstracts:

• Abstracts: Frameshifting in the expression of the E. coli trpR gene occurs by the bypassing of a segment of its coding sequence
• Abstracts: Condensin is required for chromosome arm cohesion during mitosis. Phosphorylation of RCC1 in mitosis is essential for producing a high RanGTP concentration on chromosomes and for spindle assembly in mammalian cells
• Abstracts: Evolution of the gelsolin family of actin-binding proteins as novel transcriptional coactivators. Short tandem repeats are associated with diverse mRNAs encoding membrane-targeted proteins
• Abstracts: Allozyme variation and structure of the Canarian endemic palm tree Phoenix canariensis (Arecaceae): implications for conservation
• Abstracts: Wolbachia, sex ratio bias and apparent male killing in the harlequin beetle riding pseudoscorpion. Evidence for a new feminizing Wolbachia strain in the isopod Armadilidium vulgare: evolutionary implications

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.