Eukaryotic mRNA 3' processing: A common means to different ends

Article Abstract:

The formation of the 3' end of a eukaryotic m RNA involves the hydrolysis of a single phosphodiester bond in the nascent transcript except for one unique class of mRNA, for which transcripts of the metazoan replication-dependent histone genes are required. It is indicated by the evidences that the mechanisms by which the ends of histone and polyadenylated mRNA are formed are fundamentally distinct both in the factors responsible for processing and the RNA sequence elements that direct their actions.

United States, Observations, Histones, Eukaryotes

---

Analysis of a noncanonical poly(A) site reveals a tripartite mechanism for vertebrate poly(A) site recognition

Article Abstract:

The processing of constitutive poly(A) sites is examined in detail along with the fundamental mechanisms responsible for the regulation of alternative ploy(A) site selection. The recognition of three distinct sequence elements by CFI(sub m), CPSF, and CstF suggests that vertebrate ploy(A) site definition is mechanistically more similar to that of yeast and plants than anticipated.

Vertebrates, Genetic research

---

A new yeast PUF family protein, Puf6p, represses ASH1 mRNA translation and is required for its localization

Article Abstract:

The ASH1 locasome is isolated and the associated proteins by MALDI-TOF are characterized to study the mechanism regulating ASH1 mRNA translation. Puf6p, a protein that functions in the translational control of ASH1 MRNA is proposed and this translational inhibition is necessary before localization can proceed.

Proteins

Similar abstracts:

• Abstracts: Targeting of aberrant mRNAs to cytoplasmic processing bodies. A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors
• Abstracts: Reduced representation sequencing: A success in maize and a promise for other plant genomes. Ups and downs of tissue and planar polarity in plants
• Abstracts: Evaluation of structural changes induced by high hydrostatic pressure in Leuconostoc mesenteroides. Paenibacillus polymyxa invades plant roots and forms biofilms
• Abstracts: Multicopy integration of heterologous genes, using the lactococcal group II intron targeted to bacterial insertion sequences
• Abstracts: Peptidoglycan hydrolase fusions maintain their parental specificities. Characterization of coliphage PR772 and evaluation of its use for virus filter performance testing

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.