Influence of Na+ and anions on the dimorphic transition of Candida albicans

Article Abstract:

A study was conducted on the influence of Na+ and anions on growth and dimorphic potential of the pathogenic yeast Candida albicans. The findings indicate Na+ inhibition of germ tube outgrowth at high ambient pH and that dimorphic transition is promoted by gluconate. Although the exact site of Na+ action remains unknown, the anion effects may be interpreted in terms of anion-exchanger and channel activity during the modulation of cytosolic pH.

Sodium, Sodium (Chemical element), Hydrogen-ion concentration, Anions

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A Candida albicans 37kDa polypeptide with homology to the laminin receptor is a component of the translational machinery

Article Abstract:

The coding DNA of the 37 kilodalton laminin receptor-like protein isolated from Candida albicans is isolated and characterized. In contrast to the laminin receptor found among mammals, the laminin receptor-like protein of Candida albicans appears to be a component of the ribosome. This protein is very similar to the Yst protein of Saccharomyces cerevisiae ribosome. The C. albicans laminin receptor-like protein is designated as CaYst1p.

Ribosomes

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