Pachytene exit controlled by reversal of Mek1-dependent phosphorylation

Article Abstract:

Research has been conducted on the pachytene checkpoint that requires Red1 and Mek1 meiotic chromosomal proteins. Results indicate that phosphorylated Red1 prevents exit from pachytene.

United States, Statistical Data Included, Analysis, Phosphorylation, Cell research, Cytological research

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ZIP1 is a synaptonemal complex protein required for meiotic chromosome synapsis

Article Abstract:

A screen was conducted to isolate yeast mutants defective in viable spore production, resulting in the isolation of a meiosis-specific gene, ZIP1. The gene was mapped to the right arm of chromosome IV, and mutations in the gene caused meiotic arrest at a step prior to meiosis I division. Further characterization of the gene product showed that ZIP1 is a structural component of the synaptonemal complex (SC). It is proposed that the ZIP1 protein may constitute the transverse filaments of the SC in yeast.

Yeast, Yeast (Food product)

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Imposition of crossover interference through the nonrandom distribution of synapsis initiation complexes

Article Abstract:

Melotic crossovers, in many organisms (CO) along a chromosome are non randomly distributed hence two exchanges very rarely occur close to each other, a phenomenon known as CO interference. Genetic and cytological methods are used, to investigate the interference in budding yeast and the data shows that interference is independent of synapsis.

Science & research, Yeast fungi, Yeasts (Fungi), Genetic research

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