In vivo analysis of a developmental circuit for direct transcriptional activation and repression in the same cell by a Runx protein

Article Abstract:

A developmental circuit for direct transcriptional activation and repression in the same cell by a Runx protein has been subjected to in vivo analysis . Runx proteins are implicated in acute myeloid leukemia, stomach cancer and cleidocranial dysplasia. They also control vital developmental processes in which they function as both transcriptional activators and repressors. T he developing cone cell in the Dr osophila visual system has been used to show the mechanism of positive/ negative regulations by the Runx protein Loze nge.

Science & research, Research, Cancer, Proteomics

---

Toll receptor-mediated 'Drosophila' immune response requires Dif, an NF-kB factor

Article Abstract:

Immune response as expressed by the Drosophila Toll sequence relies on Dif, the third component in NF-kB-related factors, Along with Dorsal and Relish, Dif is present in the Toll signaling pathway, and acts downstream to induce drosomycin. Dif-impaired pathways not only result in the absence of drosomycin but defensin as well, hindering immune response.

Models, Molecular biology, Immune response, Genetic research

---

The Drosophila Su(var)2-10 locus regulates chromosome structure and function and encodes a member of the PIAS protein family

Article Abstract:

Research demonstrates that mutations that alter heterochromatin-induced gene silencing bring about changes in the chromosome inheritance in Drosophila melanogaster. Data show that mutation in the gene locus Suppressor of Position-Effect Variegation affects multiple aspects of chromosome structure and function.

Statistical Data Included, Analysis, Abnormalities, Gene mutations, Gene mutation, Genetic aspects, Cell nuclei, Cell nucleus, Chromosome abnormalities

Similar abstracts:

• Abstracts: Histone deacetylase activity of Rpd3 is important for transcriptional repression in vivo. Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters
• Abstracts: Role of calcium in activity and stability of the Lactococcus lactis cell envelope proteinase. Molecular and functional analyses of the metC gene of Lactococcus lactis, encoding cystathionine beta-lyase
• Abstracts: Multivariate analysis of male mating success on morphometric traits and chromosome dosage in the grasshopper Sinipta dalmani
• Abstracts: Intra- and intermolecular events direct the propeptide-mediated maturation of the Candida albicans secreted aspartic proteinase Sap1p
• Abstracts: Transcriptional activation: risky business. H2B ubiquitylation in transcriptional control: A fact-finding mission

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.