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Haemin uptake and use as an iron source by Candida albicans: role of CaHMX1-encoded haem oxygenase

Article Abstract:

Research demonstrates that extracellular haemin is used as an iron source by Candida albicans. The iron uptake is mediated by haem oxygenase, encoded by CaHMX1, which also facilitates iron assimilation from haemin in C. albicans. Data indicate that CaHMX1 expression can be induced by iron-deprivation, by haemin, and by temperature shift from 30 to 37 C.

Author: Lesuisse, Emmanuel, Dancis, Andrew, Camadro, Jean-Michel, Santos, Renata, Buisson, Nicole, Knight, Simon
Publisher: Society for General Microbiology
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 2003
France, Usage, Oxidases, Iron compounds, Cell metabolism

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The role and relevance of phospholipase D1 during growth and dimorphism of Candida albicans

Article Abstract:

Research demonstrates that although phosphatidylcholine-specific phospholipase D1 is not required for growtth and oral infections, it produces phosphatidic acid and diacylglycerol, which are essential for the morphological development in Candida albicans.

Author: Hube, Bernhard, Hess, Daniela, Baker, Carol A., Schaller, Martin, Schafer, Wilhelm, Dolan, Joseph W.
Publisher: Society for General Microbiology
Publication Name: Microbiology
Subject: Biological sciences
ISSN: 1350-0872
Year: 2001
Germany, Statistical Data Included, Cellular signal transduction, Virulence (Microbiology), Phospholipases

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Subjects list: United States, Physiological aspects, Candida albicans
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