In vivo commitment to yeast cotranscriptional splicing is sensitive to transcription elongation mutants

Article Abstract:

The modifications of earlier published chromatin immunoprecipitation assay, is used to show that cotranscriptional splicing occurs approximately 1 kb after transcription of 3' splice site. This protects intron-containing nascent transcripts from effects of cleavage by intronic hammerhead ribozyme and suggests that high percentage of introns are recognized cotranscriptionally.

Analysis, Genetic aspects, Chromatin, Yeast fungi, Yeasts (Fungi), Catalytic RNA, Structure, RNA processing

---

Insights into the mechanism of splicing: More lessons from the ribosome

Article Abstract:

Splicing catalysts proceeds through two consecutive transesterifications involving three sites of the intron. A detailed understanding of the mechanism is necessary for ultimate explanation of all aspects of the splicing from its evolutionary origins to the regulation of alternative splicing.

Ribosomes

---

Similar abstracts:

• Abstracts: New core promoter element in RNA polymerase II-dependent transcription: sequence-specific DNA binding by transcription factor IIB
• Abstracts: Development of a lactococcal integration vector by using IS981 and a temperature-sensitive lactococcal replication region
• Abstracts: The master regulator for entry into sporulation in Bacillus subtilis becomes a cell-specific transcription factor after asymmetric division
• Abstracts: Photoreceptor ubiquitination by COP1 E3 ligase desensitizes phytochrome A signaling. The POU proteins Brn-2 and Oct-6 share important functions in Schwann cell development

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.