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Photoreceptor ubiquitination by COP1 E3 ligase desensitizes phytochrome A signaling

Article Abstract:

A study on importance of desentization of activated receptor for terminating of signal transduction is given. The results reveal that Constitutively Photomorphegenic(COP)1 acts as an E3 ligase that regulates phytochrome(phy) A signaling by targeting elimination of the phy A photoreceptor itself.

Author: Chua, Nam-Hai, Seo, Hak Soo, Watanake, Etsuku, Nagatani Akira, Tokutomi, Satoru
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2004
Ligases, Phytochrome

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The POU proteins Brn-2 and Oct-6 share important functions in Schwann cell development

Article Abstract:

Research has been conducted on Schwann cell development. The authors demonstrate that in a developmental profile these cells express Brn-2 similar to that of Oct-6, and that Brn-2 function overlaps with that of Oct-6 during the transition from promyelinating to myelinating Schwann cells.

Author: Grosveld, Frank, Jaegle, Martine, Ghazvini, Mehrnaz, Mandemakers, Wim, Riirsoo, Marko, Driegen, Siska, Levavasseur, Francoise, Raghoenath, Smiriti, Meijer, Dies
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2003
Netherlands, Analysis, Physiological aspects, Genetic aspects, Nerves, Developmental genetics, Myelin proteins, Schwann cells, Myelination

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Subjects list: Research, Genetic regulation, Genetic research
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